Lab Advisory: CDC Updates Blood Lead Reference Value
The U.S. Centers for Disease Control and Prevention (CDC) recently updated its blood lead reference value (BLRV) from 5 µg/dL to 3.5 µg/dL in response to the Lead Exposure Prevention and Advisory Committee (LEPAC) recommendation made on May 14, 2021. The BLRV is intended to identify children with higher levels of lead in their blood compared to most children, based on the 97.5th percentile of the blood lead level (BLL) distribution in U.S. children ages 1–5 years.
The new BLRV of 3.5 μg/dL may create challenges for laboratories that perform blood lead testing. Laboratories may encounter increased workloads because of additional repeat and confirmatory testing. Some laboratories may need to
For questions about the latest analytical method documentation, contact CDC’s Division of Laboratory Sciences Inorganic and Radiation Analytical Toxicology Branch.